ANATOMICAL AND METABOLICAL CHANGES INDUCED IN EXPERIMENTAL ANIMALS BY CHEMOTHERAPY

Published in Scientific Works. Series C. Veterinary Medicine, Vol. 19 ISSUE 3
Written by Raluca NEGREANU, Dan CRINGANU, Razvan NEGREANU, Cristina PREDA

The purpose of the paper is to establishing the optimal dose for each type of chemotherapy, the administration route and the time of administration depending on the circadian rithm of the body the goal of our study being to obtain minimum toxicity effect and maximum therapeutic effect

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Raluca NEGREANU, Dan CRINGANU, Razvan NEGREANU, Cristina PREDA 2013, ANATOMICAL AND METABOLICAL CHANGES INDUCED IN EXPERIMENTAL ANIMALS BY CHEMOTHERAPY. Scientific Works. Series C. Veterinary Medicine, Vol. 19 ISSUE 3, PRINT ISSN 2065-1322, 139-141.

ATAXIA – CLINICAL APPROACH

Published in Scientific Works. Series C. Veterinary Medicine, Vol. 19 ISSUE 3
Written by Cristina FERNOAGA, Mario CODREANU, Mihai CORNILA

Ataxia is defined by the loss of movement coodination and it represents one of the most important clinical signs in localizing the neurological lesion. The ataxic patient finds itself in the impossibility to coordinate head, trunk, limbs and tail position. Ataxia is a sensorial dysfunction that can only be observed when the patient moves. Ataxia is often mistaken with paresis (weakness of the limbs). Unlike paresis, ataxia only affects coordination and not muscle strength. A detailed pacient history should be provided in order to identify the cause of the ataxia. While most patients with ataxia have a primary neurological disease, it is important to know that metabolic diseases (e.g. hypoglycemia, hypocalcaemia), toxins (e.g. lead, organophosphates), and drugs (e.g. Phenobarbital, Metronidazol) can cause ataxia. Once a detailed history is obtained, physical and neurological examinations should be performed. The neurological examination enables the clinician to identify the type of ataxia. Once the type of ataxia is identified, further diagnostic tests should be performed according to the type of ataxia and the localization of the lesion. There are three types of ataxia, namely proprioceptive, cerebellar and vestibular.

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Cristina FERNOAGA, Mario CODREANU, Mihai CORNILA 2013, ATAXIA – CLINICAL APPROACH. Scientific Works. Series C. Veterinary Medicine, Vol. 19 ISSUE 3, PRINT ISSN 2065-1311, 91-94.

CARDIAC TAMPONADE SECONDARY TO INTRAPERICARDIAL TUMOR IN A DOG. CASE REPORT

Published in Scientific Works. Series C. Veterinary Medicine, Vol. 19 ISSUE 3
Written by Andrei BAISAN, Cristina BARBAZAN, Geta PAVEL, Diana MOCANU, Vlad TIPISCA, Vasile VULPE

Presence of an intrapericardial tumor can produce effusion accumulation, sometimes in a great amount, creating pressure over the myocardium and reducing the cardiac diastole. This process is called cardiac tamponade and brings together a series of changes, both in cardiac activity and the entire cardiovascular system. The pericardial effusion associated with the presence of a cardiac tumor is uncommon in dogs, with a frequency of 7%, while the cardiac tumors without pericardial effusion amount to 3% of the total cardiac diseases studied. A 12 years old male Mioritic shepherd dog was reffered to the Clinics of Veterinary Faculty of Ia

CAUDA EQUINA SYNDROME (CES) – CASE STUDY –

Published in Scientific Works. Series C. Veterinary Medicine, Vol. 19 ISSUE 3
Written by FODOR LUCIAN, SORESCU IONELA DENISA, DODOIU ADRIAN,DAN EMILIAN CONSTANTIN, CALINA NICOLAE

Cauda equina syndrome (CES) is a rare syndrome that has been described as a complex of symptoms and signs. In this study was taken one dog with paraplegia, which was treated with anti-inflammatory and analgesic. The diagnosis was using modern techniques RMI. This technique of diagnosis is one of the most effective. Dog was treated surgically by laminectomy. After 24 hours at the laminectomy high postoperative patient and two months after surgery, show no clinical neurological symptoms

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FODOR LUCIAN, SORESCU IONELA DENISA, DODOIU ADRIAN,DAN EMILIAN CONSTANTIN, CALINA NICOLAE 2013, CAUDA EQUINA SYNDROME (CES) – CASE STUDY –. Scientific Works. Series C. Veterinary Medicine, Vol. 19 ISSUE 3, PRINT ISSN 2065-1312, 95-98.

CLINICAL PRESENTATION, DIAGNOSTIC AND THERAPEUTIC APPROACH OF OCULAR MELANOSIS IN A GOLDEN RETRIEVER- CASE STUDY

Published in Scientific Works. Series C. Veterinary Medicine, Vol. 19 ISSUE 3
Written by Andra ENACHE, Iuliana IONASCU, Pip BOYDELL, Tim SCASE

Ocular melanosis represents an abnormal pigment proliferation that involves the iris, ciliary body, choroid and filtration angle leading to secondary glaucoma. This report presents a Golden Retriever with excessive pigment deposition and corneal infiltration diagnosed with uveal melanoma. A 6 year-old male Golden Retriever presented with a four-week history of corneal degeneration and excessive pigmentation of the right eye. Full ophthalmic examinations and investigations including gonioscopy, ocular ultrasound and magnetic-resonance imaging were performed. Initial ophthalmic examination showed a central area of corneal degeneration, excessive melanin deposition on the right corneal endothelium and slightly irregular pupil with iris degeneration. There were also two melanin clumps on the left corneal endothelium. Initial ultrasound showed a mass posterior to the right iris into the vitreous with blood flow on the anterior margin and bilateral vitreous degeneration. Nonsteroidal and steroidal eye drops and topical interferon-alpha were initiated. MRI scan revealed an intraocular mass ventro-laterally situated posterior to the iris likely to be consistent with uveal melanoma. Fine needle aspirates were nondiagnostic. Enucleation was initially declined and progression was monitored. Six months later, ocular ultrasound showed extensive subretinal invasion. The eye was enucleated and histopathology described uveal melanoma originated within the iris with local infiltration. A low dose oral interpheron-alpha was administered for a long term management. Clinical progress was monitored and one year follow up revealed no signs of metastasis

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Andra ENACHE, Iuliana IONASCU, Pip BOYDELL, Tim SCASE 2013, CLINICAL PRESENTATION, DIAGNOSTIC AND THERAPEUTIC APPROACH OF OCULAR MELANOSIS IN A GOLDEN RETRIEVER- CASE STUDY. Scientific Works. Series C. Veterinary Medicine, Vol. 19 ISSUE 3, PRINT ISSN 2065-1310, 85-90.

CLINICAL STAGING EXPRESSION OF CHRONIC KIDNEY DISEASE IN DOGS

Published in Scientific Works. Series C. Veterinary Medicine, Vol. 19 ISSUE 3
Written by Radu CONSTANTINESCU, Victor CRIVINEANU, Gheorghe V. GORAN, Mario D. CODREANU, Mihai CORNILA

Chronic kidney disease (CKD) is defined as the presence of functional or structural renal abnormalities, characterized by progressive loss of kidney function and/or structure. CKD includes all cases described as renal insufficiency or renal failure, but also the less advanced forms of kidney disease. Dogs of any age can be diagnosed with CKD, but it is more commonly seen in older dogs, without sex or breed predisposition, with an exception represented by inherited kidney disease. The CKD staging was based on serum creatinine values of 20 dogs, presenting a wide variety of clinical features, from clinically healthy to signs of uremic encephalopathy.

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Radu CONSTANTINESCU, Victor CRIVINEANU, Gheorghe V. GORAN, Mario D. CODREANU, Mihai CORNILA 2013, CLINICAL STAGING EXPRESSION OF CHRONIC KIDNEY DISEASE IN DOGS. Scientific Works. Series C. Veterinary Medicine, Vol. 19 ISSUE 3, PRINT ISSN 2065-1306, 68-71.

COMPARATIVE ANATOMICAL STUDY OF THE SMALL INTESTINE IN CHINCHILLA AND DOMESTIC RABBIT

Published in Scientific Works. Series C. Veterinary Medicine, Vol. 19 ISSUE 3
Written by Delia BOB, Aurel DAMIAN, Alexandru GUDEA, Cristian DEZDROBITU, Cristian MARTONOS, Florin GHIURCO, Irina IRIMESCU, Florin STAN

The species that belong to the Rodentia and Lagomorpha orders present visible differences on the morphology in the digestive tract, especially in the small intestine. The purpose of this study was to obtain a complete anatomical description of the differences between these two species and also to complete the knowledge about chinchillas. It is known that both chinchillas and domestic rabbits have lately become animal models for research, but also raised as a pets.The reseach has been carried out in the Comparative Anatomy Laboratory of the Faculty of Veterinary Medicine in Cluj-Napoca. The study was performed by dissection and macroscopic examination on five chinchillas and five rabbits. Both species have the small intestine divided into: duodenum, jejunum and ileum. In rabbits, the duodenal ampulla is not so developed as in chinchillas. In chinchillas, the ileum, the ascending segment of the large intestine and the cecal body, do not make a common block. But, in rabbits, because of a greatly developed ileocecal ligament, the ileum is attached to both of the aforementioned anatomical formations. Also, the terminal segment of the ileum of this species is represented by a sacculus rotundus, which is absent in chinchillas. Following this study, we observed differences in the morphology of the small intestine segments of these two species, that are particulary important in understanding and, also, solving the various digestive disorders that are usually found in both species.

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Delia BOB, Aurel DAMIAN, Alexandru GUDEA, Cristian DEZDROBITU, Cristian MARTONOS, Florin GHIURCO, Irina IRIMESCU, Florin STAN 2013, COMPARATIVE ANATOMICAL STUDY OF THE SMALL INTESTINE IN CHINCHILLA AND DOMESTIC RABBIT. Scientific Works. Series C. Veterinary Medicine, Vol. 19 ISSUE 3, PRINT ISSN 2065-1296, 15-18.

COMPARATIVE BIBLIOGRAPHIC STUDY REGARDING THE COLLATERALS OF ASCENDING AORTA AND AORTIC CROSS IN HUMANS, SWINE AND EQUINE

Published in Scientific Works. Series C. Veterinary Medicine, Vol. 19 ISSUE 3
Written by Flaviu TUNS, Alina IURCUT, Ioana CHIRILEAN, Carmen CRIVII, Aurel DAMIAN

The blood is a fluid absolutely indispensable to life. It is responsible for the transportation of all nutrients to cells and tissues in the body. A very important segment in this process represents the cardiovascular system, also known as the circulatory system. The main blood vessel from the body is the aorta. This is the widest blood vessel which branches into several different arteries to serve all tissues in the body. Since the requirements for nutrients and oxygen differ according to species, we considered interesting to realise a synthesis of aortic branches, namely its ascending part and the aortic arch (Arcus aortae) in humans, swine (Sus scrofa domestica) and equine (Equus caballus). The present study involves the systematic evaluation of each vascular aortic segment focusing on: the confirmation of the presence of ascending aorta and aortic arch; similarities regarding the number and origin of collateral arteries. Following the review of the literature we found numerous differences in the studied species. First, we noted the absence of ascending aorta segment in pigs compared with humans and horses, where it is present. Further we identified differences regarding the coronary arteries (Aa. coronaria), differences that implies the origin of the artery openings. There were also different numbers of collaterals branches in the aortic arch: 3 in human, 2 in swine and only one in equine. Another interesting observation was the origin of carotid arteries from pigs and horses which is represented by the bi-carotid trunk, segment that is missing in humans.

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Flaviu TUNS, Alina IURCUT, Ioana CHIRILEAN, Carmen CRIVII, Aurel DAMIAN 2013, COMPARATIVE BIBLIOGRAPHIC STUDY REGARDING THE COLLATERALS OF ASCENDING AORTA AND AORTIC CROSS IN HUMANS, SWINE AND EQUINE. Scientific Works. Series C. Veterinary Medicine, Vol. 19 ISSUE 3, PRINT ISSN 2065-1302, 47-52.

COMPARATIVE MACROSCOPIC ASPECTS OF REGENERATION IN SKIN LESIONS TREATED WITH PLASMA RICH IN PLATELETS

Published in Scientific Works. Series C. Veterinary Medicine, Vol. 19 ISSUE 3
Written by Alina IURCUT, Aurel DAMIAN

Plasma rich in platelets (PRP) is a biological material that contains high levels of platelets, blood cells that are rich in growth factors involved in the initiation of the healing process. PRP can be used on a large number of lessions, including those induced on the skin. The efficiency of the product was tested on an experimental lot of rabbits of the same age, wheight and gender. Lesions consisting of incisions and excisions were induced on the skin of the rabbits of both a control and a test group, in the dorsal thoracic region. This sites were then subsequently treated with PRP every 7 days over a period of 4 weeks, in the test group only. The procedure was performed by perilesional inoculations with activated plasma, watching the comparative evolution of the healing process within the 2 groups: control and test. The results revealed an acceleration of the healing process in the tested group. Positive characteristics were noted regarding: retraction of the wound, the presence and thickness of the crust, peripheral erythema, hair regeneration and the visibility more or less pronounced of the scars. In this study we have found beneficial aspects after using platelet-rich plasma, consisting of an acceleration of the healing process and a pronounced anti-inflammatory effect, features that recommend its use in the skin lesions.

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Alina IURCUT, Aurel DAMIAN 2013, COMPARATIVE MACROSCOPIC ASPECTS OF REGENERATION IN SKIN LESIONS TREATED WITH PLASMA RICH IN PLATELETS. Scientific Works. Series C. Veterinary Medicine, Vol. 19 ISSUE 3, PRINT ISSN 2065-1316, 114-118.

COMPARATIVE STUDIES OF THE NEUROCRANIUM FOR DIFFERENT SPECIES OF WILD ANIMALS

Published in Scientific Works. Series C. Veterinary Medicine, Vol. 19 ISSUE 3
Written by Alexandra BLENDEA, Cristian Sergiu BARDAS, Flaviu TUNS , Aurel DAMIAN

The study has been carried out in order to assess the anatomic characteristics specific to the neurocranium in some wild species: wolf (Canis lupus), marten (Martes foine) and fox (Vulpes vulpes). The differentiation of the neurocranium is made very difficult in the mentioned species, for reason which it is important to know the morphological peculiarities of the skeleton of these wild carnivorous animals. For this study, we have used corpses of animals of different genders and ages, originated in woodlands and zoos from Transylvania. They have been processed through known anatomic techniques until bone parts have been obtained in the Laboratory of Comparative Anatomy within the Veterinary Medicine Faculty of Cluj- Napoca. The methods used during the dissection and the processing of the bone parts consisted of visual observation and macroscopic analysis of each and every bone. The sagittal crest and the mastoid process are well developed at the three species studied. Two side holes have been noticed on each side of the occipital condyle at wolf, while these do not exist at marten and fox. The zygomatic process of frontal bone is little developed at marten, the supraorbital hole does not exist in all the examined species, and the external protuberance of the occipital has been only noticed at fox and marten, as a distinct entity. The study has highlighted some characteristics of the bones which are part of the neurocranium, that will lead to exact assessment of the skull descent species in wolf, fox and marten.

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Alexandra BLENDEA, Cristian Sergiu BARDAS, Flaviu TUNS , Aurel DAMIAN 2013, COMPARATIVE STUDIES OF THE NEUROCRANIUM FOR DIFFERENT SPECIES OF WILD ANIMALS. Scientific Works. Series C. Veterinary Medicine, Vol. 19 ISSUE 3, PRINT ISSN 2065-1295, 11-14.

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