Published in Scientific Works. C Series. Veterinary Medicine, Vol. LVIII ISSUE 4
Written by CLINICAL, ULTRASOUND AND LABORATORY CHANGES IN CUSHING SYNDROME IN DOGS
Dogs` adrenal pathology is dominated by Cushing syndrome, mostly by iatrogenic origin or neoplasic glandular lesions. Clinical evaluation were performed following the classic screening protocol and additional hematological and biochemical investigations (liver/kidneys function), hormonal determinations (basal cortisol or after stimulation tests, i.e. suppression) and ultrasound exams. In our study were included 18 dogs with Cushing syndrome (hyperadrenocorticism). From clinical point of view the main registered clinical signs were bulimia, polyuria-polydipsia syndrome, abdominal ptosis, hepatomegaly, calcinosis and/or cutaneous hyper pigmentation, bilateral symmetrical alopecia). The biochemical blood profile registered changes (increased ALT and AST activity, hyperlipidemia, decreased serum urea levels, hyperglycemia) and urinary (diluted urine, proteinuria). Ultrasound reveals in case of affected adrenal glands appears as distinct structures, flattened shape, appearance lobe, located cranio-medial kidney, caudal of the mesenteric and celiac artery and cranial of the renal artery and the right (lower) prior to renal vein and cranial right kidney. According to their topography, size and structure the ultrasound changes were very useful for the diagnosis of the diseases related to adrenomegaly and changing their echogenicity and echostructure.
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adrenal glands
