Scientific Works Series C. Veterinary Medicine

PRINT ISSN 2065-1295, ISSN-L: 2065-1295, ISSN CD: 2343-9394,ISSN ONLINE 2067-3663
 

THE DEVELOPMENT OF A PRECLINICAL MODEL FOR OSTEOINTEGRATION OF DENTAL IMPLANTS - A PILOT STUDY

Published in Scientific Works. Series C. Veterinary Medicine, Vol. LXIX, Issue 2
Written by Diana-Larisa ANCUȚA, Maria CRIVINEANU, Cristin COMAN

Functional tooth replacement and bone regeneration are areas of interest in modern dentistry and dental implant research involves increased attention to osteointegration. The aim of the study was to develop a small, inexpensive and reproducible animal model for testing dental implants. Fifteen male Wistar rats, 20 weeks old, average weight of 400 grams were included in the study. They were subjected to a rigorous bone support preparation protocol so that the maxillary first premolar was extracted from the left half arch. After a period of 30 days, necessary for the bone refilling of the dental alveolus, the radiological examination was performed. Then a surgical intervention was performed to mount the titanium implants of an adapted size. Clinically, the evolution was favorable, with no signs of discomfort or oral infection. At the radiological evaluation, optimal bone regeneration could be observed. necessary to ensure a suitable place for implant mounting. The implantation procedure was laborious due to the limited working area. However, rats are proving to be suitable animal models for implant-related studies or innovative treatments administered under pathological conditions.

[Read full article] [Citation]

The publisher is not responsible for the opinions published in the Volume. They represent the authors’ point of view.

© 2019 Scientific Works Series C. Veterinary Medicine. All Rights Reserved. To be cited: Scientific Works Series C. Veterinary Medicine.

Powered by INTELIDEV