Published in Scientific Works. Series C. Veterinary Medicine, Vol. LXIX, Issue 2
Written by Oana POP (COZMA), Carmen Dana ȘANDRU, Diana OLAH, Gheorghiță DUCA, Mariana RUSU, Aurel VASIU, Emoke PALL, Cristian VĂLEANU, Marina SPÎNU
The active principles extracted from plants prove to be useful in preventing or treating various diseases through their influence at molecular level. This potential of plants could reduce the negative effects of existing therapies due to lesser side effects and the results of bioavailability studies are encouraging. Hydro-alcoholic Salvia glutinosa L. extracts were examined for their antioxidant potential, anti-bacterial activity and in vitro immune stimulating effects. The dry aerial part of the plant (herba) was used for these experiments, after minced and solubilized in ethanol and also in aqueous solution. The antioxidant capacity was investigated by free radical scavenging effect over 1,1-diphenyl l-2-picrylhydrazyl (DPPH) radical, the antimicrobial effect by the Kirby Bauer radial diffusion test and the immune stimulating effect by tests on whole blood cultures. The results indicated a stronger antioxidant capacity (RSA% 88.89), antibacterial effect (G - E. coli, P. aeruginosa, x = 12 mm < G+, S. aureus, ATCC/clinical strains, x = 23 mm) and immune stimulation of the ethanol extract compared to the aqueous one. These results indicated the plant as a potential complex source to be implemented in alternative therapy.
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