PRINT ISSN 1222-5304, ISSN-L: 2065-1295, ISSN CD: 2343-9394,ISSN ONLINE 2067-3663
 

INTRAVESICAL ADMINISTRATION OF CYTOSTATIC IN A DOG WITH URINARY BLADDER CARCINOMA - CASE STUDY

Published in Scientific Works. Series C. Veterinary Medicine, Vol. LXVI, Issue 2
Written by Catalin MICSA, Dorin ȚOGOE, Gina GÎRDAN, Maria RoxanaTURCU, Cristina PREDA, Andrei TANASE

A 9-year-old spayed female mixed Pit Bull Terrier of 33.2 kg was referred with a complaint of stranguria, pollakiuria, hematuria, and abdominal pain of 5 weeks duration, not responding to treatment. The results of physical examination were unremarkable. A abdominal ultrasound revealed a large mass on the wall of the urinary bladder. The regional lymph nodes and the other abdominal organs present normal sonographical features. Thoracic radiography showed no evidence of metastatic disease. Blood samples have been taken for biochemistry work, CBC and urine samples. The dog underwent a cystoscopy, histopathological examination of the retrieved specimen reveal T2N0M0 TCC (muscle-invasive transitional cell carcinoma). Due to the mass location on the wall of the bladder, surgery was not an option. Considering the result of the investigation, chemotherapy treatment has been applied: intravesical every 2-week cycle consisted of alternating epirubicin and 5-fluorouracil and intravenous holoxan. The treatment was well tolerated with no occurrence of any side effects. The abdominal ultrasound was repeated every 1 month and showed no progression of the disease.

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