IS THE CHROMATIC PUPILLARY RESPONSE (CPR) A FOOTHOLD IN THE DIAGNOSIS OF OPHTHALMOLOGICAL AND NEUROLOGICAL DISORDERS?

Published in Scientific Works. C Series. Veterinary Medicine, Vol. LVIII ISSUE 4
Written by Iuliana Ionașcu, Adina Bădicu – 6th year student

Recent studies have shown that a light stimuli of a certain intensity and wavelength can influence the pupillary response. The aim of this research is to evaluate the CPR and to establish its role in the differential diagnosis of ophthalmological and neurological disorders. CPR is part of the patients’ ophthalmological clinical examination protocol brought to the clinic of the Bucharest Faculty of Veterinary Medicine. These patients (dogs and cats) had one or more ophthalmological symptoms (progressive loss of vision, mydriasis, anisocoria, blindness) and/or neurological symptoms (nystagmus, torticollis, circling, ataxia, proprioceptive deficits). CPR examination was performed in the darkroom, using the IRIS-VET device. CPR is positive in healthy animals, represented by miosis. Negative, delayed or incomplete CPR (mydriasis) to the red light (630 nm, 200 kcd/m2) reveals an impairment of the photoreceptor cells of the retina, lesions encountered in retinal detachments, retinal dysplasia or progressive retinal atrophy. CPR absence to the blue light (480 nm, 200 kcd/m2) provides information about the optic nerve and retinal ganglion cells. Negative CPR both to the red and blue light was present in glaucoma and optic chiasm disorders. The study showed that CPR is a fast and easy method to differentiate between ophthalmological and neurological disorders.

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Ionașcu I., Bădicu A. 2012, IS THE CHROMATIC PUPILLARY RESPONSE (CPR) A FOOTHOLD IN THE DIAGNOSIS OF OPHTHALMOLOGICAL AND NEUROLOGICAL DISORDERS?. Scientific Works. C Series. Veterinary Medicine, Vol. LVIII ISSUE 4, PRINT ISSN 1222-5304, 212-219.


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