THE USE OF MEDETOMIDINE AND BUPRENORPHINE FOR PREMEDICATION, KETAMINE FOR INDUCTION AND ISOFLURANE TO MAINTAIN GENERAL ANESTHESIA IN RABBITS. CASE STUDIES

Published in Scientific Works. Series C. Veterinary Medicine, Vol. LIX (1)
Written by Alexandru Cosmin TUTUNARU, Florin LEAU, Alexandru SONEA, Charlotte SANDERSEN

The aim of this study was to assess the level of analgesia and safety of this aesthetic protocol. Many other anaesthetic protocols presented in scientific works are not enough detailed regarding their safety or their analgesic predicted effects. For this study we anesthetized three healthy rabbits. Two of them suffered a standard orchiectomy procedure and one suffered an orthopaedic intervention on humerus. All three received the same anaesthetic protocol. They were premedicated using medetomidine 0.25 mg/kg. After 10 minutes the rabbits were induced using ketamine 15 mg/kg subcutaneous. For analgesia we administered buprenorphine 0.03 mg/kg subcutaneous and meloxicam 0.6 mg/kg. Anaesthesia was maintained with isoflurane administered by facemask 1-1.5% in pure oxygen. During anaesthesia we assessed respiratory and cardiac parameters using a pulse-oximeter. After analysing our results we concluded that this protocol gives a predictable level of analgesia sufficient for most of procedures, even orthopaedic surgeries, and that our subjects were free of any cardio-respiratory secondary effects during anaesthesia.

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Tutunaru A. C., Leau F., Sonea A., Sandersen C. 2013, THE USE OF MEDETOMIDINE AND BUPRENORPHINE FOR PREMEDICATION, KETAMINE FOR INDUCTION AND ISOFLURANE TO MAINTAIN GENERAL ANESTHESIA IN RABBITS. CASE STUDIES. Scientific Works. Series C. Veterinary Medicine, Vol. LIX (1), ISSN 2065-1295, 81-84.


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