Published in Scientific Works. Series C. Veterinary Medicine, Vol. LXVIII, Issue 1
Written by Gheorghița DUCA, Carmen Dana ȘANDRU, Diana OLAH, Mariana RUSU, Constantin CERBU, Marina SPÎNU, Florinel BRUDAȘCĂ, Emoke PALL, Adrian POTÂRNICHE, Aurel VASIU
Vaccination against contagious agalactia of sheep, an OIE declarable, highly economically impacting disease, is the most widespread method to reduce the disease prevalence. This research monitored the influence of M. agalactiae S/94 and AG6, two commercial vaccines for sheep, on systemic humoral immunity in two flocks of ewes (n1=95, n2=220, respectively). Blood was sampled from both flocks before and one month after the booster vaccination and subjected to total Ig (24%o zinc sulphate precipitation test) and circulating immune complexes’ (4.2% polyethylene glycol precipitation test) evaluation. There were significant differences (p<0.001-0.004) in total Ig levels for both strains (7.68±2.63 and 23.68±5.7 for S/94 and 11.1±3.58 and 26.11±3.4 Vernes degrees for AG6, before and after the vaccination, respectively), but no differences in CIC concentrations (p=0.08 and p=0.59, for S/94 and AG6) between the samplings or the strains (p=0.342) were found. A strong positive correlation (r=0.889, p<0.05) was established between total Ig and CIC levels for the AG6 but not the S/94 strain, therefore other influential factors (individual, adjuvant, frequency of vaccination) should be investigated.
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