Scientific Works Series C. Veterinary Medicine

PRINT ISSN 1222-5304, ISSN-L: 2065-1295, ISSN CD: 2343-9394,ISSN ONLINE 2067-3663
 

POTENCY EVALUATION OF TWO COMMERCIAL VACCINES AGAINST CONTAGIOUS AGALACTIA OF SMALL RUMINANTS

Published in Scientific Works. Series C. Veterinary Medicine, Vol. LXVII, Issue 1
Written by George MOGOŞ, Mihai DANEŞ, Doina DANEŞ

Immunoprophylaxis is the most affordable, effective and eco-friendly tool, which recommends it as the first option to control contagious agalactia in small ruminant flocks. The purpose of this study was to evaluate the immune response toward two marketed vaccines. Both products contain Mycoplasma agalactiae inactivated with formalin, on aluminum hydroxide gel. The trial has been carried out on a flock of 700 sheep. Each vaccine was administered to 250 animals according to the manufacturer instructions and 200 animals were in the control group. Serum samples were collected on vaccination days (0 and 21) and post vaccination, at 30, 90, 180 and 360 days. The immune response was assessed using a commercial indirect ELISA kit for antibody detection. Antibody titers increased rapidly after vaccination, reached the highest level between 21 and 30 days and declined after 180 days. No statistically significant differences in titers were identified between the two vaccines.

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