Scientific Works Series C. Veterinary Medicine

PRINT ISSN 1222-5304, ISSN-L: 2065-1295, ISSN CD: 2343-9394,ISSN ONLINE 2067-3663
 

A COMPARATIVE CLINICAL AND PARACLINICAL EVALUATION OF THE EFFECTS OF POLYSPECIFIC AVIAN IMMUNOGLOBULIN Y IN FIV+/- CATS

Published in Scientific Works. Series C. Veterinary Medicine, Vol. LXVI, Issue 1
Written by Teodora-Diana SUPEANU, Alexandru SUPEANU, Lucica SIMA, Viviana ROMAN, Dragoş COBZARIU, Stelian BĂRĂITĂREANU, Laura MENCHETTI, Doina DANEŞ

Feline Immunodeficiency Virus (FIV) infection represents a viral immunosuppressive condition that predominantly affects the immune system, having no curative therapeutic options. The present research focused on the biological and physical effect of the use of poly-specific avian immunoglobulin Y (IgY) on some immune molecules of FIV infected cats, especially on gamma-globulins and white blood cells, as well as on how this therapy can amend or improve the quality of life of infected cats. The polyspecific avian immunoglobulin Y was used to treat two groups of feline patients: 10 patients infected with FIV and 10 patients free of the disease. The patients were monitored via blood samples collected on days 0, 20 and 40. The samples were used for testing the biochemical profile, CBC, WBC and the plasma concentration of 10 cytokines: Fas, IFNγ, IL-1β, IL-2, IL-4, IL-5, IL-8, IL-10, IL-12p40 and RANTES. The study also attempted to establish the eventual side effects associated with the suppressed immune system of FIV infected cats.

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