Scientific Works Series C. Veterinary Medicine

PRINT ISSN 1222-5304, ISSN-L: 2065-1295, ISSN CD: 2343-9394,ISSN ONLINE 2067-3663
 

HEMATOLOGICAL AND PLASMA BIOCHEMICAL VALUES IN FOUR SPECIFIC PATHOGEN-FREE MICE STRAINS PRODUCED IN THE ANIMAL FACILITY AT CANTACUZINO INSTITUTE, BUCHAREST

Published in Scientific Works. Series C. Veterinary Medicine, Vol. LXIV, Issue 1
Written by Cristin COMAN, Ene VLASE, Angelica DINU

Laboratory mice are still the most used animal in research and animal experiments. In most experiments, knowledge of hematology and biochemistry data base is essential to achieving quality results and used the research results. Cantacuzino Institute from Bucharest is the most important provider of laboratory mice in Romania and therefore making it available to the users the hematological and biochemical physiological data of the mice strains from his animal facility was an ethical obligation. Hematologic analysis and biochemical from blood were performed in 4strains of mice (2 inbred and 2 outbred) in both sexes and age groups, in dynamics. Hematologic analyses were made from whole blood and biochemical ones from blood plasma. The results showed differences between the lines, sexes and age categories. The results obtained can be used by the researchers on selecting the mice strains according to the purpose of the research and according to the values of the hematological and biochemical parameters. The results thereby helping to reduce stress in animals.

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