Scientific Works Series C. Veterinary Medicine

PRINT ISSN 1222-5304, ISSN-L: 2065-1295, ISSN CD: 2343-9394,ISSN ONLINE 2067-3663
 

PHENOTYPES OF FLUOROQUINOLONE RESISTANCE IN PSEUDOMONAS AERUGINOSA ISOLATES FROM A ROMANIAN HOSPITAL

Published in Scientific Works. Series C. Veterinary Medicine, Vol. LXII, Issue 1
Written by Oana – Alexandra CIOCAN (MOŢCO), Alper ÇIFTÇI, Yagmur KOÇAK, Mihai CARP – CĂRARE, Mihai MAREŞ, Andreea – Paula COZMA, Ioana CRIVEI, Eleonora GUGUIANU, Cristina RÎMBU, Carmen - Valentina PANZARU, Cătălin CARP – CĂRARE

Due to the increased frequency of multidrug-resistant bacterial strains isolated from infectious processes, a constant analysis of their sensitivities to the antibiotics currently used in therapy is required. The aim was to follow the evolution of the resistance phenomena for Pseudomonas aeruginosa strains isolated from infections. Pseudomonas aeruginosa is a current concern for clinicians and epidemiologists due to the intrinsic resistance to several classes of antibiotics, acquiring resistance and limiting therapeutic actions. It is a microorganism of major importance in the nosocomial infections developed both in the human and veterinary spaces. The tests were part of a more extensive study which was aimed at the correlating, identifying common resistance profile of P. aeruginosa strains of human and animal originated. Considering the pathogenic action of this bacterial species both for humans and animals, the data obtained can support the establishment of a mutual strategy to prevent and combat the action of strains having multiple resistance to antibiotics. Efflux transporters have a considerable role in the multidrug resistance (MDR) of P. aeruginosa, an important nosocomial pathogen. The lack of some antibiotics, active towards P. aeruginosa, makes the control of infection the most important measure against the MDR- P. aeruginosa strains. The study batch included strains of P. aeruginosa, out of which only the antibiotic-resistant strains, 61 strains respectively, were selected for the phenotypic characterization in fluoroquinolones.

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