Published in Scientific Works. Series C. Veterinary Medicine, Vol. LIX (1)
Written by Galina SIMEONOVA
The aim of the experiment was to study changes in blood gases, electrolytes, acid-base and some coagulation parameters occurring during long lasting anaesthesia and strangulation obstruction of the small intestine in horses. Five healthy ponies were used for that purpose. They were submitted to 9 hours isoflurane anaesthesia with CRI of dexmedetomidine and ketamine. Strangulation obstruction of the small intestine was performed for 6 hours for histomorphometric investigations and was restored with enteroanastomosis afterward. Arterial and venous blood samples were taken in three periods and investigated parameters were measured. Instead of periodic IPPV oxygenation progressively decreased judged from lowered PaO2 and saturation with time. Moreover, a respiratory acidosis developed at 3rd hour and went deep at 9th hour. With regard to coagulation system alterations affected only D-dimer. Increase in D-dimer values corresponded with elevation of blood lactate level. Long lasting anaesthesia and abdominal surgery does not impaired significantly oxygenation and coagulation in healthy horses but could contribute to further worsening of already compromised functions in colic horses.
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blood gases
