Published in Scientific Works. Series C. Veterinary Medicine, Vol. LXXI, Issue 1
Written by Rodica-Maria GHIȚĂ, Ioana-Bogdana NICOLA, Cristian Ionuț FLOREA, Andrei RĂDULESCU, Crina Alexandra BOANCĂ, Alexandru Bogdan VIȚĂLARU, Alina ȘTEFĂNESCU
A 1-year-old, 20 kg, intact female mixed-breed dog was admitted to the clinic for a nephrology consultation following ethylene glycol ingestion. Upon examination, the patient displayed severe hypertension (202/154 to 205/156 mmHg, measured by oscillometric method), abdominal pain, conjunctivitis, advanced dehydration, a rectal body temperature of 38.9°C, and dry mucous membranes. Laboratory tests revealed elevated BUN 151 mg/dL, CRE 10.2 mg/dL, PHOS 9.9 mg/dL, and GLU 123 mg/dL. Urinalysis showed a borderline proteinuria (UPC 0.5-2.0), pH of 5.0, and microalbumin ≥25 mg/L. To preserve renal function, haemodialysis was indicated as extracorporeal renal replacement therapy. Over eight days, four haemodialysis sessions were performed following the placement of a central venous catheter under light sedation with oxygen therapy supplementation. These therapeutic interventions, including intensive fluid management, were crucial in improving renal function. Significant biochemical improvements were observed: BUN decreased to 66 mg/dL, CRE to 3.7 mg/dL and PHOS to 8.0 mg/dL. Additionally, Ca levels rose from 11.3 mg/dL to 13.5 mg/dL. This case emphasizes the importance of timely intervention in acute kidney injury following ethylene glycol toxicity. Continued monitoring is essential for long-term renal recovery.
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