Scientific Works Series C. Veterinary Medicine

PRINT ISSN 2065-1295, ISSN-L: 2065-1295, ISSN CD: 2343-9394,ISSN ONLINE 2067-3663
 

RESEARCH ON INFLAMMATORY ANEMIA INDUCED BY CORTICOSTEROIDS

Published in Scientific Works. Series C. Veterinary Medicine, Vol. LXX, Issue 2
Written by Adrian RĂDUȚĂ, Oana Diana MIHAI, Simona NICOLAE, Ioana Nicole REU

Research was conducted on 10 CD1 laboratory mice, non-consanguineous strains, divided into two groups of 5 individuals per group. The body weight of individuals ranged from 20 to 30 grams. Both groups were given the same favourable climate, humidity and light conditions. The forage diet consisted of pelleted rodent feed, with feed and water administered at libitum. The control group was injected at the beginning of the experimental period with 1 ml NaCl subcutaneously and the experimental group with 1 ml dexamethasone i.e. 4 mg subcutaneously. The duration of the experiment was 14 days. At the end of the experiment, decreases in erythrocyte count, haemoglobin, haematocrit and increases in derived erythrocyte constants were observed. The results of the leukocyte formula showed an increase in the number of polymorphonuclear cells and a decrease in the other categories of leukocytes in the experimental group.

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