Published in Scientific Works. Series C. Veterinary Medicine, Vol. LXX, Issue 2
Written by Dalma PIVARIU, Mircea MIRCEAN, Nechita-Adrian OROS, Alexandra MUREȘAN, Zsofia DARADICS, Robert STĂNILĂ, Naomi LATIȘ, Melania Ioana CRIȘAN, Sabrina ARDELEAN
Acetaminophen is one of the most used analgesic agent for the relief of acute and chronic pain in humans. Equine analgesia poses a common challenge to clinicians, so acetaminophen could be considered as an alternative to common non-steroidal anti-inflammatory drugs used in horses. The purpose of this research was to observe the safety of treatment with acetaminophen, and it was carried out at the USAMV Cluj-Napoca. In order to initiate treatment with acetaminophen, a dose of 20 mg/kg was administered orally, once every 12 hours, for a period of 14 days, in two horses of approximately 500 kg, aged 16 and 17 years, from
Lipizzan breed. We administered the commercial product Paracetamol Terapia, containing 500 mg acetaminophen each tablet, for human use. The horses in this study were monitored throughout the treatment, from a clinical point of view, and complementary examinations were made (the gastric mucosa was monitored with gastroscopy). The haematological analyses were performed with the Abacus Junior Vet5, and for the biochemical analyses a Skyla vb1+ analyser was use. In this study during the treatment, no significant haematological or biochemical changes were
observed after acetaminophen administration.
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