Published in Scientific Works. Series C. Veterinary Medicine, Vol. LXX, Issue 1
Written by Cristian Ionuț FLOREA, Crina Alexandra BOANCĂ, Andrei RĂDULESCU, Alina ȘTEFĂNESCU, Alexandru Bogdan VIȚĂLARU
A 5 years old Shar Pei female, diagnosed with acute kidney injury was referred for hemodialysis therapy. The dog was presented with lethargy, lack of appetite, severe weight loss, dehydration (7-10%) and pale mucous membranes. To prevent exacerbation of preexisting comorbidities, in order to sedate a renal patient, a safe anesthesia protocol requires understanding the kidney disease pathology and hemodialysis therapy implications. A central venous catheter (CVC) was placed under a light sedation with additional oxygen therapy. Sedation was induced intravenously with alfaxalone (Alfaxan® multidose), on a peripheral catheter. The dose was titrated until full relaxation of the patient was observed. During the procedure, there were no major hemodynamics changes in the patient. Alfaxalone is a short-acting and rapid duration anesthetic with minimal or no cardiovascular consequences. When given titrated to effect, it represents the best choice for short sedation in central venous catheterization for acute renal patients undergoing hemodialysis.
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