Published in Scientific Works. Series C. Veterinary Medicine, Vol. LXIX, Issue 1
Written by Laura DARIE, Elvira GAGNIUC, Alice RADULESCU, Ana Simina MIHAI, Andreea Diana GONTOIU, Emilia CIOBOTARU-PIRVU
Mediastinal lymphoma in cats affects the lymph nodes in the cranial mediastinum and/or the thymus. The tumor comprises 10-20% of feline lymphomas. Males appear to be overrepresented. A 2-year-old neutered male Scottish Fold cat with hypertrophic cardiomyopathy treated according to the results of the medical investigation was presented for a second opinion consult. X-ray examination showed a gigantic neoplastic mediastinal mass, and the ultrasound examination revealed a right-sided deviation of the heart axis. Due to the poor prognosis, the cat was euthanized, and the necropsy was performed. Mediastinal T-cell lymphoma with neoplastic invasion into the pericardium and discreetly into the epicardium was diagnosed based on gross pathology, histopathology, and immunohistochemistry. The left atrium presented endocardial fibroelastosis, while the ventricular myocardium showed intercellular edema, myocardocyte laceration, vacuolar and hyaline degeneration, and necrosis in small, isolated areas. Additionally, the lung displayed diffuse collapse, edema, and congestion.
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