Published in Scientific Works. Series C. Veterinary Medicine, Vol. LXVIII, Issue 1
Written by Maria Roxana TURCU, Ruxandra PAVEL, Cătălin MICŞA, Ruxandra COSTEA, Lucian IONIŢĂ
The aim of this systematic review is to examine the effects of different anesthetic drugs and protocols on hepatic functions. The liver is a very important organ since it is directly involved in biotransformation of the drugs used in anesthesia. Comprehensive understanding of anesthetic drugs and their effects on hepatic functions remains fundamental to a successful anesthesia. Understanding the connections that exist between anesthetic drugs and liver function remains essential for a safe anesthesia both during the surgery and in the post-operative period. Almost all anesthetic drugs depend on hepatic biotransformation into their metabolites that can be transported and excreted by the kidneys. If the liver enzymes are altered, the biotransformation of the drugs will be decreased and the recovery from the anesthesia prolonged.
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