Published in Scientific Works. Series C. Veterinary Medicine, Vol. LXVII, Issue 1
Written by Roxana-Mariana IGNĂTESCU (ȚÎMPĂU), Ana-Maria GOANŢĂ, Andreea-Bianca BOFAN, Alexandra BRAICA, Natalia RĂDULEA, Lucian IONIŢĂ
This paper underlines the role of kidney biopsy in the diagnosis of various kidney diseases in dogs. Even though it is an invasive method, kidney biopsy is often required to establish a definitive diagnosis and an accurate prognosis. Its use should always be considered after weighing the indications and potential complications. Several techniques are used to obtain kidney samples, such as percutaneous renal biopsy (blind or palpation technique or using ultrasound guidance, keyhole technique, laparoscopic biopsy) and surgical biopsy. Once the method has been chosen, the renal sample should only be obtained from the renal cortex. This procedure requires a patient that is stable to undergo general anesthesia or deep sedation. Kidney biopsy samples may be evaluated using light microscopy and special stains, transmission electron microscopy and immunofluorescence to obtain a diagnosis of certainty and to guide treatment options.
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