Published in Scientific Works. Series C. Veterinary Medicine, Vol. LXV, Issue 2
Written by Ana-Maria COMAN, Emilia BALINT, Dragos-Constantin COMAN, Nicolae MANOLESCU
Wanting to study a special topic in the field of comparative oncology, the component part of the new global medical concept One Health, we proposed to develop the cytomorphological basis of adenopathies caused by the chronic parasitic infestations with Fasciola hepatica, Echinococcus granulossus or Dicrocelium lanceolatum. Our research have unfolded over 4 years, on a number of 267 animals: 82 horse, 147 sheep, 16 swine and 22 cattle, which presented, at post-mortem examination, one or more adenopathies, alongside the characteristic lesions of a chronic parasitic disease. From these animals we harvested the lymph nodes with lesions and we have done smears to examine the populations of the cellular system of immunity. Through this screening we succeeded to make a real "movie" of cytomorphological lesions, transposing, step by step, the transformations of lymphnodal cell populations which are persistently stimulated by the hyperantigenity induced by the chronic parasitism, from the stage of chronic lymphadenitis, to the malignant prelymphoma.
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