Published in Scientific Works. Series C. Veterinary Medicine, Vol. LXI
Written by Georgeta DINESCU, Ioana Cristina FUNDĂȚIANU, Andrei TĂNASE, Elvira CONDRUȚ, Teodoru SOARE, Manuella MILITARU
Canine cutaneous histiocytic proliferative disorders are increasingly seen in general practice and they pose as both diagnostic and therapeutic challenges for veterinary clinicians. This study aims to evaluate and describe the epidemiology and morphological features of the histiocytic proliferative disorders in dogs as well as to emphasize the importance of the cytological examination in the diagnostic approach. The study was conducted over a period of 5 years (2008-2012) in the Department of Pathological Anatomy of the Faculty of Veterinary Medicine Bucharest and comprises a total of 130 cases of dogs with cutaneous lesions that had been diagnosed with cutaneous histiocytic proliferative disorders. The cytologically examined samples were obtained by fine needle technique (78%), either with or without aspiration, and by surgical biopsy (22%). The slides were obtained by sliding, imprinting or squeezing and either classical or quick May-Grünwald Giemsa (MGG) staining techniques were used. 26 cases were both cytologically and histologically examined. During this period a number of 3855 dogs were specifically examined out of which 1381 (35.8%) had cutaneous lesions. Of the 1381 dogs presenting cutaneous lesions, 130 (9.4%) were diagnosed with different histiocytic lesions. Of the 130 cases evaluated in this study, 80 (61.5%) were males and 50 (38.5%) were females, indicating that males are more prone to developing this type of lesions. The most frequently affected body regions were the trunk (37%) and the limbs (37%). 9.2% of the total number of cases had multicentric lesions. After cytological examination and according to the latest classification of the histiocytic diseases in dogs, the following lesions were diagnosed: canine cutaneous histiocytoma (54%), histiocytic sarcoma (29%), malignant histiocytosis (6.2%), reactive histiocytosis (5.4%) and atipical histiocytoma (5.4%).
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