Published in Scientific Works. Series C. Veterinary Medicine, Vol. LXI
Written by Dan CRÎNGANU, Rǎzvan NEGREANU, Raluca NEGREANU
Lymphomas are malignant monoclonal cell proliferation having the starting point in the organized lymphoid tissue (spleen, thymus, limfocentrii) or the diffused lymphoid tissue (gut-Payer boards and tonsils) The different types of lymphomas are common regarding the symptoms, but differs depending on changes that occur at the cellular level and proliferating cell type, proliferation type and how they echo through out the body. Age and sex of the animals have an importan role because this form of cancer is identified by the age of 2 (years) with maximum frequency between 5 and 7 years old, but also with cases at age 10 in both sexes. Breeds that are most often affected are: Boxer, Scottish Terrier, Airedale Terrier, German Shepherd, Poodle, Rottweiler and Golden Retriver. Purebred dogs are more sensitive than half breeds. The color black appears to be a factor due to absorption of ultraviolet radiation, dogs with dark fur being exposed to both skin tumors and NHL. Lymphoma diagnosis begins with clinical examination revealing enlarged lymph nodes and sometimes the presence of general signs of illness: fever, cluster, weight loss, dyspnea, anorexia, anemia. Lymphosarcoma classification is based on location, histological criteria and immunophenotypic features.
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