Published in Scientific Works. Series C. Veterinary Medicine, Vol. 19 ISSUE 4
Written by COMPARATIVE ELECTROPHORESIS OF SERUM PROTEINS IN RATS TREATED WITH TWO ORALLY DELIVERED LECTINS
Electrophoresis is a common technique to assess the serum or plasma proteins patterns associated with different physiological and pathological conditions in humans and animals. The aim of this study was to evaluate serum protein fractions and their changes induced by potato shoots and bean pods lectins’ administration to healthy Wistar rats. Both lectins induced an albumins (%) increase, accompanied by a slight decrease in α1 and α2 globulins. The most important change was recorded for β-globulins that significantly decreased in the case of both lectins administration. Serum protein electrophoresis demonstrated that the studied lectins, even orally delivered, survived proteolytic attack during gastrointestinal passage, were absorbed, and induced functional alterations of different organs.
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