COMPARISON OF BENIGN AND MALIGNANT MAMMARY TUMORS IN DOGS THROUGH RAMAN SPECTROSCOPY: TWO CLINICAL CASES

Published in Scientific Works. Series C. Veterinary Medicine, Vol. LXIII, Issue 2
Written by Raluca M. MUNTEANU, L.O. SCOICARU, Manuella MILITARU, Elvira GAGNIUC, Catalin MICSA, Dorin TOGOE, Alexandru B. VITALARU, M.I. RUSU, M. TAUTAN, B. CHIRICUTA, M. V. UDREA, Alexandru SONEA, C-E-A. GRIGORESCU, Alin I. BIRTOIU

This paper reports on two clinical cases where Raman spectroscopy has been employed for diagnostic in dog mammary tumour surgery. The comparison between histopathology and SERS results proves that the spectral markers can be used to distinguish between malignant or normal tissue. By comparing results from histopathology and Raman spectroscopy we set up a fast and affordable diagnostic tool using the marker-like Raman bands of carotenoids and respectively interfacial water. Application of the described technique is useful in comparative studies of canine and human mammary cancer.

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MUNTEANU R.M., SCOICARU L.O., MILITARU M., GAGNIUC E., MICSA C., TOGOE D., VITALARU A.B., RUSU M.I., TAUTAN M., CHIRICUTA B., UDREA M.V., SONEA A., GRIGORESCU C-E-A., BIRTOIU A.I. 2017, COMPARISON OF BENIGN AND MALIGNANT MAMMARY TUMORS IN DOGS THROUGH RAMAN SPECTROSCOPY: TWO CLINICAL CASES. Scientific Works. Series C. Veterinary Medicine, Vol. LXIII, Issue 2, ISSN 2065-1295, 85-90.


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