THE MONITORING AND RESPONSE OF TRANSFUSION REACTIONS TO GLUCOCORTICOID THERAPY

Published in Scientific Works. Series C. Veterinary Medicine, Vol. LXIII, Issue 1
Written by Catalin Constantin IVASCU, Alexandru SONEA

The transfusion reactions represents one of the major risks of transfusion therapy, regardless of the blood product used, whole blood, erythro-concentrate or frozen plasma. This paper presents the evolution of transfusion reactions and treatment of 60 dogs during the period 2014-2016 monitored in the Clinics of the Faculty of Veterinary Medicine in Bucharest. The clinical signs, CBC, biochemistry were observed for all dogs as the animals came to the clinics. The treatment provided has a base content of glucocorticoid mixture of drugs and complementary symptomatic therapy. The glucocorticoid therapy refers to the usage of hemi-succinate hydrocortisone at the beginning of each transfusion and at the administration of Prednisolone at the end. The glucocorticoid combo therapy was used in all transfusions, regardless of the product or sub-product of blood being used. For 70% of the cases was used whole blood, for 20% erythro-concentrate and for 10% plasma. The data processed using the parameters above shows a decreased number of transfusion reactions when used the glucocorticoid drug combo on the 50% of the case load in comparison to the other 50% which did not receive the glucocorticoid therapy prior to transfusion. This study shows that the glucocorticoid combo therapy might be helpful in a variety of cases in which the pathology presented allows the usage of glucocorticoid therapy.

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IVASCU C.C., SONEA A. 2017, THE MONITORING AND RESPONSE OF TRANSFUSION REACTIONS TO GLUCOCORTICOID THERAPY. Scientific Works. Series C. Veterinary Medicine, Vol. LXIII, Issue 1, ISSN 2065-1295, 115-118.


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