THE COMPARATIVE THERAPEUTIC EFFICACY OF ANTIMICROBIALS IN PIGS INFECTED WITH MYCOPLASMA HYOPNEUMONIAE
Published in Scientific Works. Series C. Veterinary Medicine, Vol. LXII, Issue 2
Written by Roman PEPOVICH, Branimir NIKOLOV, Krasimira GENOVA, Kalin HRISTOV, Radka TAFRADJIISKA-HADJIOLOVA, Elena NIKOLOVA, Georgi STOIMENOV
Respiratory diseases are current health problem for pig. Very often they have polietiological base which triggers defined Porcine Respiratory Disease Complex (PRDC). One of the main and permanent etiologic agents in PRDC is Mycoplasma hyopneumoniae, the causative agent of enzootic pneumonia in pigs. The disease is widespread in Bulgaria, inflicting major economic damage, resulting in high morbidity, poor feed conversion, reduced average daily gains, cost of therapy and immunization. These indicators determine treatment as necessary and inevitable in control of mycoplasma infection. The purpose of this study was to compare the therapeutic potential of enrofloxacin and florfenicol in industrial pig farms in Bulgaria. The study was conducted in pig farm breeding and fattening, with laboratory proven acute form of enzootic pneumonia. It was conducted on 260 growing pigs divided into two experimental groups. The first group was treated with enrofloxacin injective at a dose of 1 ml/10 kg., for three days, and the second with florfenicol, at a dose of 1 ml/20 kg., intramuscularly twice in 48 hours. Received clinical and epidemiological data give reason to assume that the tested schemes are effective in the control of enzootic pneumonia. As a result of the treatment to stabilize by the clinical condition of the pigs, normalization of indicators of blood and limiting morbidity and mortality. The resulting high therapeutic effect in patients treated with enrofloxacin pigs - 89.6 % and respectively florfenicol - 75.6 %, presented both as equivalent antibiotic in the treatment of enzootic pneumonia.