TRANSFER FACTORS FOR ENDOCRINE DISRUPTING COMPOUNDS FROM FEED TO MILK

Published in Scientific Works. C Series. Veterinary Medicine, Vol. LVIII ISSUE 3
Written by Mirela Miclean, Cecilia Roman, Ioan Stefan Groza

Toxic compounds, such as organochlorine pesticides (OCPs) and polychlorinated biphenyls (PCBs) are ubiquitous in the environment, thus indirectly in animals feed. The transfer of these compounds from animal feed to food products contributes to the human exposure, through consumption. OCPs and PCBs are highly persistent, biocumulative and exercise a wide range of toxic effects, including endocrine system disrupting, being considered as a new class of nonsteroidal xeno-estrogens. In this study, the transfer factors (TFs) for 19 OCPs and 7 PCBs have been evaluated for the quantification of their transfer from cows’ fodder to milk. The samples (milk and feed from cow’s diet) were collected in two villages from Maramures County, Romania. The compounds OCPs and PCBs were analyzed using gas-chromatography coupled with electron capture detection after solvent extraction. Among the OCPs, all the HCH isomers were detected in all the investigated samples, the highest concentration were obtained for α-HCH. All the isomers DDTs (except 2,4’-DDD) were determined, with highest concentration for 4,4’-DDE. The obtained results showed that the TFs ranged between 0.03-0.28, the highest value was recorded for hexachlorobenzene and the lowest for lindane. High values were determined also, for dieldrin (0.25) and for heptachlor (0.23).

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Miclean M., Roman C., Groza I. S. 2012, TRANSFER FACTORS FOR ENDOCRINE DISRUPTING COMPOUNDS FROM FEED TO MILK. Scientific Works. C Series. Veterinary Medicine, Vol. LVIII ISSUE 3, PRINT ISSN 1222-5304, 348-355.


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