STUDIES ON THE THERAPY WITH GONADOTROPIN-RELEASING HORMONE (GnRH) AND HUMAN CHORIONIC GONADOTROPIN (hCG) IN GENITAL DISORDERS IN BITCHES

Published in Scientific Works. C Series. Veterinary Medicine, Vol. LVIII ISSUE 4
Written by Mihai Cristian Popescu, Maria Crivineanu, Mario Darius Codreanu

Infertility in bitch is characterized by a variety of clinical manifestations depending on the disorders of reproductive system. The purpose of this study was to asses the efficacy of gonadotropin-releasing hormone (GnRH) and human chorionic gonadotropin (hCG) in the treatment of prolonged estrus caused by follicular cysts in bitch. In this study, there were diagnosed 10 bitches with prolonged estrus having as etiology the presence of follicular cysts. The intensity of clinical signs was studied and vaginal smears were performed, resulting in high percentages of keratinized cells in bitches with follicular cysts. Determinations of estrogen and progesterone hormones were made, the presence of follicular cysts being suspected based on the high values of estrogen and duration of estrus. Duration of estrus signs ranged between 32-76 days, progesterone concentration was between 1.3-3.4 ng/ml, while the concentration of estrogen hormones ranged between 141.5-379.5 pg/ml. Based on the high values of estrogen hormones, the presence of keratinized cells, the duration of estrus and the age of bitch it was suspected the existence of follicular cysts. The efficacy of hormonal treatment (GnRH and/or hCG) was monitored by determining the values of estrogen and progesterone hormones, the results being correlated with the interpretation of vaginal smears and clinical manifestations. Following hormonal treatments, in 7 bitches clinical signs of estrus disappeared in 4-6 days, while 3 bitches still presented the clinical manifestations characteristic to estrus phase after the treatment.

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Popescu M. C., Crivineanu M., Codreanu M. D. 2012, STUDIES ON THE THERAPY WITH GONADOTROPIN-RELEASING HORMONE (GnRH) AND HUMAN CHORIONIC GONADOTROPIN (hCG) IN GENITAL DISORDERS IN BITCHES. Scientific Works. C Series. Veterinary Medicine, Vol. LVIII ISSUE 4, PRINT ISSN 1222-5304, 316-321.


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